[Whitepaper] Advanced Analytical Approaches for Accelerated Development of Gene Therapy Products

Gene and cell therapies offer tremendous potential for treating unmet medical needs; however, successful development of these advanced therapeutic approaches is extremely challenging, largely because of their complexity. Characterizing and quantitating specific structural attributes and assessing criticality of those that influence quality, efficacy and safety is essential. Evaluation includes delivery to target tissues, protein expression in vivo and eventual correlation with clinical outcomes to be able to advance both individual gene therapy candidates and the emerging underlying vector/gene platforms.

Download the White Paper and learn about:
  • The latest approaches to characterization and quantitation of gene therapy vector proteins
  • How advanced LC-MS based analytics are being applied to elucidate and quantitate the attributes of vector proteins that are critical to efficacy and quality
  • The influence of specific molecular attributes on efficacy and how high-resolution data can be used to guide, de-risk and improve development of complex gene therapy products

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