June 6, 2018

FierceBiotech Executive Breakfast
CAR-T 2.0: INNOVATION NEVER STANDS STILL

Boston Convention & Exhibition Center / Room 205ABC / Meeting Level 2

About

CAR-T 2.0: Innovation Never Stands Still

After getting the first ever approvals in CAR-T in 2017 for Novartis and Gilead/Kite, you would think that the industry could rest on its laurels. But we’re only at the beginning of the CAR-T journey, and everyone is already thinking about CAR-T 2.0, aimed at making the next wave of drugs safer, more effective, more accessible for patients, while also deepening our understanding of its place within the immune system and the fight against cancer.

Companies are already looking for better ways to tweak the cell therapy technology; here, we talk to the pioneers of the next-gen CAR-T field about the challenges inherent in shaping a new field through clinical research; the new methodologies they are using in their quest; and what lessons we’ve already learned from current CAR-T drugs.

Speakers

Opening Remarks: Lindsay McNair, MD, MPH, MSBioethics

Chief Medical Officer
WIRB-Copernicus Group (WCG)
Lindsay McNair, MD, MPH, MSBioethics is the Chief Medical Officer for WCG.  In this role, she oversees the physician team within the WCG IRBs, and provides consultation to organizations related to protocol design, regulatory compliance, human subject protection, and ethical policy development. Previously, she was a consultant providing medical guidance on clinical development strategies and study designs.  Before becoming a consultant, Dr. McNair was the medical lead for the telaprevir development program at Vertex Pharmaceuticals, with oversight of the phase 1-3 studies.  

Michael Kalos, Ph.D.

Vice President, Janssen Immuno-Oncology and Oncology Cell Therapy
Janssen Pharmaceutical Companies of Johnson & Johnson
Michael Kalos, PhD is Vice President, Janssen Immuno-Oncology and Oncology Cell Therapy, for the Janssen Pharmaceutical Companies of Johnson & Johnson. Michael has responsibility for further enhancing the scientific strategy required to deliver the Janssen portfolio of immuno-oncology and cell-based oncology therapeutics, and build a robust pipeline of next-generation compounds. Michael is a recognized international key opinion leader in the fields of immunotherapy, T cell therapy, and biomarkers.

Dr. Sadik Kassim

Chief Scientific Officer
Mustang Bio
Dr. Sadik Kassim is Chief Scientific Officer of Mustang Bio, and previously served as its Vice President of Process and Analytical Development. Sadik has played key roles at the forefront of CAR-T, including Head of Analytical Development in Novartis’ Cell and Gene Therapies Unit, where he worked on the Kymriah™ BLA filing in pediatric ALL and DLBCL, and a National Cancer Institute biologist involved in early research that led to Kite’s Yescarta™ for lymphoma.

Frederic Ors

Chief Executive Officer
IMV, Inc.
Frederic Ors has served as the Chief Executive Officer of IMV, Inc. since April 2016. As CEO, he has led the transformation of IMV into a leading clinical-stage immune oncology company with world-class collaborators and a strong scientific foundation.  He has more than 20 years of experience in the biopharmaceutical industry.  Before joining IMV, Fred spent 14 years at Medicago.  He has also served as second Vice-Chair of the Vaccine Industry Committee of Biotech Canada. 

Dr. Angela Shen

Chief Medical Officer
Nkarta Therapeutics
Dr. Angela Shen, M.D., M.B.A is currently serving as Chief Medical Officer at Nkarta Therapeutics and Arcellx, Inc. Angela has extensive experience in clinical development and business development, with prior leadership roles at Arvinas, Novartis, Exelixis, and Johnson & Johnson. During her tenure at Novartis, Angela was instrumental in establishing the program as well as leading the clinical and operational teams for CTL019 (CART-19; KymriahTM), which became the first FDA-approved CAR-T therapy.

Closing Remarks: Andreas Weiler

Global Business Unit Head of Emerging Technologies
Lonza Pharma & Biotech
Andreas Weiler is the Global Business Unit Head of Emerging Technologies at Lonza where he oversees the Cell and Gene Therapy Contract Manufacturing businesses. Before joining Lonza he worked for Sigma Aldrich (SAFC), another leading CDMO (Contract Development and Manufacturing Organization) to the Pharma/biotech industries, for over 17 years where he held several positions as Business Director and finally as the Head of Strategic Marketing to the organization.

Since 2015, when Andreas joined Lonza, Cell and Gene Therapy sales have more than doubled and the manufacturing footprint expanded significantly to cover the globe with facilities in North America, Europe and Asia. Andreas holds a PhD in Organic Chemistry from University of Freiburg and an MBA degree.

FirstName LastName

Job Title
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FirstName LastName

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Moderator: Amirah Al Idrus

Editor
FierceBiotech
Amirah Al Idrus is an editor with the FierceMarkets Life Sciences group covering medtech and biotech research. Before joining Fierce, Amirah completed a master's degree in journalism at the University of Maryland, where she concentrated in online and multimedia journalism. She has covered issues ranging from Maryland politics and local business to finance in state prisons. When she's not working, Amirah spends her time playing rugby, running around D.C., visiting museums, and baking (and eating) pies. She can be reached at [email protected].

schedule

6:45 AM - 7:15 AM: Check-in, Networking, and Breakfast Buffet
7:15 AM - 8:30 AM: Panel Discussion

sponsors

Pricing

Regular Rate

$129 per person

Note: If you are not a registered attendee for the BIO International Convention, you must pick up a badge at the BIO registration in East Registration, Exhibit Level before arriving to Room 205ABC.

location

FAQ

Parking at the Boston Convention Center

Valet parking ($30) is available during most events. To access from Summer Street, turn onto East Side Drive and the valet area will be immediately on your right. We accept cash and all major credit cards.
BCEC South Parking Lot:

To self-park in the BCEC South Lot, from Summer Street, turn onto East Side Drive, drive past the valet area, and continue straight along the side of the building. At the end of the building, make a right and go down the ramp. At the bottom of the ramp, turn left and you will see the entrance to the South Parking lot in front of you. Parking rates are $18 for regular sized vehicles and $36 for oversized vehicles.

Please note: Parking is limited at the BCEC and is available on a first come, first served basis. On certain events if the South Lot is full, attendees may be directed to an offsite parking lot.

Yes, a full breakfast buffet will be served from 6:45 AM - 8:30 AM

Attendee substitutions may be made on or before May 30, 2018. Please submit a written request by email to Ashley Secondini at [email protected].

Due to the nature of this event, we are unable to provide refunds. Attendee substitutions may be made on or before May 30, 2018. Please submit a written request by email to Ashley Secondini at [email protected].